Lecture 09

Class Lecture Notes

Summary:

We started on proteins and amino acids today. We went over the basic of amino acids and their make ups. All of them except for Proline has an alpha carbon center with R group, carboxylic acid, and amino group hanging off of it. We have to know all 22 different amino acids (20+2 rare). Their stereochemistry and how it affects the protein making… etc, etc.

One Response to “Lecture 09”

  1. chris mole Says:

    If the -OH is on the right its D not. This is an awesome study tool.

Lecture 09

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Today’s Lecture Notes

Summary:

A lot of what we did today rehashs the electrophilic aromatic substitution. We went over how nitro substituent would affect whether the incoming E+ would go to the ortho, meta, or para position. We also talked about how multiple subsituents would affect where the incoming E+ is going.

The next part is the nucleophilic substitution. The mechanism is a bit different and requires an electron withdrawing subsituent already on the aromatic ring. First, the (Nuc-) would attack a site with good leaving group (Cl-), then the double bond withdraws to the carbon with the EWG forming a carboanion. Then, the carbonanion comes down and kick the leaving group out, reforming the aromaticity.

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